Overview · 4-minute read
Injections, gels, pellets, patches: the trade-offs in one page.
All four delivery methods work — they differ in cost, dose stability, and daily hassle more than in effectiveness. Here is the honest one-paragraph version of each.
Injections
The least expensive and most adjustable option, usually weekly or twice-weekly at home. Downsides: needles, and levels that peak and dip between doses unless the schedule is tuned. This is where most careful prescribers start.
Daily gels
Steadier day-to-day levels and no needles, but they cost more, absorb inconsistently in some men, and carry a real transfer risk — skin contact can pass testosterone to partners and children before it dries.
Pellets
Implanted under the skin every 3–6 months in a minor office procedure. Convenient — but the dose cannot be adjusted once implanted, and if side effects appear, you wait them out or have the pellets removed.
Patches
Daily, steady, needle-free. The trade-off is frequent skin irritation, which is why patches are the least commonly chosen of the four.
Deciding between methods? USTRT's full comparison covers dosing schedules, monthly costs, switching between methods, and questions to ask about each.
See the full comparison on USTRT →Sources
- American Urological Association — "Evaluation and Management of Testosterone Deficiency: AUA Guideline." 2018.
- Journal of Clinical Endocrinology & Metabolism — Bhasin S, et al. Endocrine Society Clinical Practice Guideline. 2018.